Some antidepressant medications can cause weight gain, especially the older tricyclic antidepressants (TCAs) such as Tryptizol, Saroten, and Clomipramine; as well as newer drugs such as Remeron (Mirtazapine). Lithium (for manic-depressive disorder) often causes weight gain. The most common antidepressants known as SSRI’s (for example Citalopram and Sertraline) usually don’t impact weight significantly. More on depression 

For even more impressive effects on body composition: aim for exercise forms which elicit a positive hormonal response. This means lifting really heavy things (strength training), or interval training. Such exercise increases levels of the sex hormone testosterone (primarily in men) as well as growth hormone. Not only do greater levels of these hormones increase your muscle mass, but they also decrease your visceral fat (belly fat) in the long term.
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One, it's impossible to "spot reduce." While you can target certain areas of your body in terms of building up the muscles in that area, you can't decide to just lose weight in your stomach, or your thighs, or your rear. It doesn't work that way. You can't remove subcutaneous body fat from specific areas of the body by doing exercises that target those areas. Doing hundreds of crunches will certainly strengthen your abs, but that won't reduce the amount of fat stored in your torso.
This study divided 54 obese patients up into 2 groups, both of which were put on lower calorie diets (meaning a caloric deficit was present) and fed similar percentages of protein, fat and carbs. HOWEVER, one group was given a more balanced diet comprised of meals that contained protein, fat and carbs, while the second group had their carb and fat calories separated so they were not eaten together in the same meal. Guess what happened? They all lost the same amount of weight and body fat. Why? Because the manner in which you combine foods, organize your meals and consume your daily calories isn’t what causes fat loss. A caloric deficit is.

When fat loss is the goal, the one macronutrient I like to be aware of is protein. Aim for 0.6 – 0.7 grams of protein per pound* of bodyweight as a daily average. If you’re obese, then eat approximately 0.6-0.7 grams per pound of your general-target bodyweight. For example, if you weigh 210 pounds and know 160 pounds is a healthy body weight for you, then eat 0.7 grams per pound of that 160 pound target (in this example that would be about 96-112 grams of protein).


Vine recommends beginning by taking note of your weight, body fat percentage and muscle mass using one of the above methods. Watch how these figures change over a few days – is your weight and muscle mass dropping, but your body fat increasing, despite regular workouts, for example? ‘That could mean you’re eating too many carbs and not enough protein to sustain your muscle,’ Vine says. Tweak your regime accordingly and monitor the numbers again. Repeat until it’s solely fat coming off.
Simply take a good hard look at your diet, make a few modifications you can stick with and get your body moving. Not sure where you stand on diet? Write down everything you eat this week, then compare it to the list above and see where you could have made better choices. Don’t beat yourself up though, learning how to lose stomach fat fast is a process. Simply find areas to improve and work on them next week.
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