As chronic obstructive pulmonary disease (COPD) advances, about 35% of patients experience severe weight loss called pulmonary cachexia, including diminished muscle mass.[31] Around 25% experience moderate to severe weight loss, and most others have some weight loss.[31] Greater weight loss is associated with poorer prognosis.[31] Theories about contributing factors include appetite loss related to reduced activity, additional energy required for breathing, and the difficulty of eating with dyspnea (labored breathing).[31]

At its core, it's about math. Calories in, calories out, right? Not so fast. (Before we get started, stop believing these other myths about burning fat and building muscle.) About 50 percent of women say that within six months they gain back any weight they've managed to ditch. And more than a quarter have dieted so many times they've lost track of the number. So what's up with the yo-yoing?
The Mayo Clinic Diet is designed to help you lose up to 6 to 10 pounds (2.7 to 4.5 kilograms) during the initial two-week phase. After that, you transition into the second phase, where you continue to lose 1 to 2 pounds (0.5 to 1 kilogram) a week until you reach your goal weight. By continuing the lifelong habits that you've learned, you can then maintain your goal weight for the rest of your life.
Lastly, as I indicated, all my lifts are going up, but my weight (and even LBM, assuming my scale is even remotely accurate) so is it fair to say that strength gains are not directly related to muscle gains? Is this the “beginner” phase that you speak of frequently? The scale would indicate that muscle is going down….. But my presses, squats, deadlifts are all up.