This could be because the body increases insulin secretion in anticipation that sugar will appear in the blood. When this doesn’t happen, blood sugar drops and hunger increases. Whether this chain of events regularly takes place is somewhat unclear. Something odd happened when I tested Pepsi Max though, and there are well-designed studies showing increased insulin when using artificial sweeteners.
Unsurprisingly, the results showed that nothing had happened to the weight of the women receiving calcium or the placebo. However, the group which took the multivitamin lost more weight – about 3 kg more – and improved their health markers. Among other things, their basal metabolic rate (the rate at which the body burns calories when at rest) increased.

Eating enough protein – around 25% of calories – can probably help. Some supplements, like glycine and BCAAs might also be useful. But what helps even more is exercise. Even though it doesn’t cause weight loss on its own, exercise is still a powerful tool for making sure that weight changes (loss or gain) go in the direction you want (fat loss/muscle gain) instead of turning into a problem (muscle loss/fat gain).

Basically, the effect of exercise on our weight is vastly overrated. That’s why it’s only number 15 on this list. There are other things you need to take care of first. It’s not a good idea to eat bad food, drink sugar water (so-called “sports drinks”) or be on medications which force you to exercise for hours daily just to compensate. Metaphorically that’s like digging a hole, into which you put your ladder, on which you stand and paint the basement-level windows of your house.

Most of us eat quickly, chewing each bite just a few times, which means we consume more food than we realize. Slow down and try to eat more mindfully: In a study, people who chewed each bite 40 times ate almost 12 percent less than those who chewed just 15 times. When we chew longer, our bodies produce less ghrelin, a hormone that boosts appetite, and more of the peptide hormones that are believed to curb hunger. (Discover five ways your hormones might be messing with your appetite.)
You don't really want dessert, but your friends are having some, and they're urging you to join them. So you give in and order a piece of tiramisu. Sorry to say it, but you've just committed sociotropy, aka people pleasing-a behavior that can make you gain weight. In a recent study, women and men who regularly experienced negative emotions like guilt, anxiety, and anger, and were impulsive and disorganized, tended to be heavier than those who were more even-keeled.
Some antidepressant medications can cause weight gain, especially the older tricyclic antidepressants (TCAs) such as Tryptizol, Saroten, and Clomipramine; as well as newer drugs such as Remeron (Mirtazapine). Lithium (for manic-depressive disorder) often causes weight gain. The most common antidepressants known as SSRI’s (for example Citalopram and Sertraline) usually don’t impact weight significantly. More on depression